Periodontal care may improve systemic inflammation

Periodontal Infection, Systemic Inflammation, and Insulin Resistance

OBJECTIVE Adverse microbial exposures might contribute to diabetogenesis. We hypothesized that clinical periodontal disease (a manifestation of microbial exposures in dysbiotic biofilms) would be related to insulin resistance among diabetes-free participants. The roles of inflammatory mediation and effect modification were also studied. RESEARCH DESIGN AND METHODS The continuous National Heal...

Periodontal treatment may reduce levels of systemic inflammation markers associated with atherosclerotic profile.

Key Study Factor The criteria for selecting the trials were as follows: (1) Human subjects with periodontitis; (2) intervention group receiving periodontal treatment (PT) and a non-intervention group receiving no periodontal treatment (NPT); and (3) outcome variables must be clinical CVD parameters and/or markers of atherosclerosis and CVD risk, including markers of systemic inflammation and th...

Systemic inflammation in cardiovascular and periodontal disease: comparative study.

Epidemiological studies have implicated periodontal disease (PD) as a risk factor for the development of cardiovascular disease (CVD). These studies addressed the premise that local infection may perturb the levels of systemic inflammatory mediators, thereby promoting mechanisms of atherosclerosis. Levels of inflammatory mediators in the sera of subjects with only PD, only CVD, both diseases, o...

Emergency Medicine specialty May Improve Patient Satisfaction

Stress increases periodontal inflammation

This study aimed to examine the effect of chronic restraint stress (RS) on the severity of experimental periodontal disease in rats. A total of 32 male Sprague Dawley (SD) rats were divided into four groups: i) Rats receiving two treatment regimens, chronic stress induced by movement restriction in acrylic cylinders for 1-1.5 h daily and induction of experimental periodontal disease, using a ny...